TABLE 2.
Top 20 highly expressed genes of each cluster.
| Gene | Cluster | p-value | Log FC |
| Dspp | Ameloblast (I) | 4.59E-21 | 2.7 |
| Cyp26a1 | Ameloblast (I) | 5.08E-14 | 2.3 |
| Col9a3 | Ameloblast (I) | 2.01E-13 | 2.2 |
| Stac3 | Ameloblast (I) | 3.21E-11 | 2.0 |
| Acp5 | Ameloblast (I) | 1.99E-04 | 1.9 |
| Fxyd4 | Ameloblast (I) | 2.45E-10 | 1.9 |
| Plod2 | Ameloblast (I) | 1.22E-09 | 1.8 |
| Calb1 | Ameloblast (I) | 2.12E-09 | 1.8 |
| H2-Eb1 | Ameloblast (I) | 2.95E-02 | 1.8 |
| Fxyd3 | Ameloblast (I) | 5.52E-09 | 1.8 |
| Wnt6 | Ameloblast (I) | 7.98E-08 | 1.7 |
| Ndrg1 | Ameloblast (I) | 4.78E-07 | 1.6 |
| Nrn1l | Ameloblast (I) | 2.56E-06 | 1.6 |
| tg_DsRed | Ameloblast (I) | 2.89E-06 | 1.5 |
| Acpp | Ameloblast (I) | 6.39E-06 | 1.5 |
| Cd24a | Ameloblast (I) | 4.57E-06 | 1.5 |
| Shh | Ameloblast (I) | 2.15E-05 | 1.5 |
| Krt14 | Ameloblast (I) | 6.61E-06 | 1.5 |
| Krt5 | Ameloblast (I) | 3.03E-05 | 1.4 |
| Ambn | Ameloblast (II) | 1.71E-26 | 2.5 |
| Amelx | Ameloblast (II) | 8.15E-25 | 2.5 |
| Chst1 | Ameloblast (II) | 5.36E-18 | 2.1 |
| Acpt | Ameloblast (II) | 3.64E-17 | 2.1 |
| Lama3 | Ameloblast (II) | 1.39E-16 | 2.1 |
| Aplp1 | Ameloblast (II) | 9.29E-17 | 2.0 |
| Cd55 | Ameloblast (II) | 5.48E-15 | 2.0 |
| Galnt12 | Ameloblast (II) | 2.95E-14 | 1.9 |
| Lamb3 | Ameloblast (II) | 6.66E-14 | 1.9 |
| Enam | Ameloblast (II) | 2.76E-13 | 1.8 |
| Arsb | Ameloblast (II) | 1.57E-11 | 1.7 |
| Cntnap2 | Ameloblast (II) | 1.57E-11 | 1.7 |
| Itpr1 | Ameloblast (II) | 1.89E-10 | 1.6 |
| Hba-a2 | Ameloblast (II) | 2.77E-06 | 1.6 |
| Cystm1 | Ameloblast (II) | 1.26E-09 | 1.6 |
| Fam46a | Ameloblast (II) | 3.00E-09 | 1.5 |
| Itpripl2 | Ameloblast (II) | 4.50E-08 | 1.4 |
| Lamc2 | Ameloblast (II) | 2.68E-07 | 1.4 |
| Fam3c | Ameloblast (II) | 3.35E-07 | 1.4 |
| Epcam | IEE/OEE | 6.17E-13 | 2.1 |
| Mt2 | IEE/OEE | 2.93E-12 | 2.1 |
| Pitx2 | IEE/OEE | 1.88E-09 | 1.8 |
| Shh | IEE/OEE | 4.49E-09 | 1.8 |
| Pdgfa | IEE/OEE | 1.86E-08 | 1.7 |
| Ube2c | IEE/OEE | 5.90E-08 | 1.7 |
| Ccnd1 | IEE/OEE | 1.05E-07 | 1.7 |
| Hmgb2 | IEE/OEE | 6.19E-07 | 1.6 |
| Cenpf | IEE/OEE | 2.51E-06 | 1.6 |
| Cenpa | IEE/OEE | 2.01E-06 | 1.6 |
| Sostdc1 | IEE/OEE | 1.53E-06 | 1.5 |
| Stmn1 | IEE/OEE | 1.39E-06 | 1.5 |
| Lgals7 | IEE/OEE | 3.49E-06 | 1.5 |
| Cyp26a1 | IEE/OEE | 5.96E-06 | 1.5 |
| 2810417H13Rik | IEE/OEE | 4.98E-06 | 1.5 |
| Pfdn4 | IEE/OEE | 4.51E-06 | 1.5 |
| Krt17 | IEE/OEE | 1.18E-05 | 1.4 |
| Cldn10 | IEE/OEE | 6.64E-05 | 1.4 |
| Smc4 | IEE/OEE | 1.64E-05 | 1.4 |
| Tfrc | SI/SR | 1.06E-40 | 4.6 |
| Chchd10 | SI/SR | 1.53E-27 | 3.8 |
| Slc4a4 | SI/SR | 4.50E-27 | 3.9 |
| Atp1b1 | SI/SR | 1.58E-25 | 3.9 |
| Nectin3 | SI/SR | 1.29E-24 | 3.7 |
| Igfbp2 | SI/SR | 8.53E-23 | 3.6 |
| Krt15 | SI/SR | 6.69E-21 | 3.5 |
| Gnrh1 | SI/SR | 7.28E-20 | 3.5 |
| Sgk1 | SI/SR | 1.84E-19 | 3.4 |
| Dapl1 | SI/SR | 1.87E-19 | 3.5 |
| Dsc3 | SI/SR | 3.65E-19 | 3.4 |
| Barx2 | SI/SR | 8.93E-19 | 3.3 |
| Snap91 | SI/SR | 9.99E-19 | 3.3 |
| Tnc | SI/SR | 1.44E-18 | 3.4 |
| Atp1b3 | SI/SR | 1.77E-17 | 3.2 |
| Tst | SI/SR | 6.21E-16 | 3.1 |
| Rbbp8 | SI/SR | 1.90E-14 | 3.0 |
| Fam13a | SI/SR | 1.39E-13 | 2.9 |
| Dsp | SI/SR | 1.42E-13 | 2.9 |
| Dmp1 | Odontoblast | 1.12E-27 | 4.9 |
| Smpd3 | Odontoblast | 1.97E-50 | 4.5 |
| Plac8 | Odontoblast | 9.56E-40 | 4.0 |
| Bglap | Odontoblast | 1.63E-20 | 3.9 |
| Sct | Odontoblast | 4.33E-24 | 3.9 |
| Bglap2 | Odontoblast | 1.00E-17 | 3.9 |
| Dkk1 | Odontoblast | 1.61E-28 | 3.8 |
| Bglap3 | Odontoblast | 7.34E-18 | 3.7 |
| Sgms2 | Odontoblast | 1.69E-29 | 3.6 |
| Ifitm5 | Odontoblast | 1.32E-24 | 3.4 |
| Dcn | Odontoblast | 4.01E-15 | 2.6 |
| Cox4i2 | Odontoblast | 2.05E-13 | 2.5 |
| Gchfr | Odontoblast | 4.74E-12 | 2.4 |
| Omd | Odontoblast | 2.12E-11 | 2.3 |
| Ibsp | Odontoblast | 3.60E-06 | 2.3 |
| Lum | Odontoblast | 6.64E-12 | 2.3 |
| Ptn | Odontoblast | 1.09E-11 | 2.3 |
| Serpinf1 | Odontoblast | 1.10E-10 | 2.2 |
| Cdkn1c | Odontoblast | 1.24E-08 | 2.0 |
| Mpz | Mesenchyme | 3.67E-06 | 2.8 |
| Ogn | Mesenchyme | 1.13E-28 | 2.8 |
| Sfrp2 | Mesenchyme | 4.95E-23 | 2.7 |
| Mmp13 | Mesenchyme | 5.13E-23 | 2.7 |
| Spp1 | Mesenchyme | 1.24E-11 | 2.7 |
| Bmp3 | Mesenchyme | 1.13E-24 | 2.6 |
| Sfrp4 | Mesenchyme | 4.93E-23 | 2.6 |
| Tagln | Mesenchyme | 5.72E-24 | 2.6 |
| Col12a1 | Mesenchyme | 1.62E-22 | 2.5 |
| Ncam1 | Mesenchyme | 2.26E-22 | 2.5 |
| Postn | Mesenchyme | 4.58E-20 | 2.4 |
| Col3a1 | Mesenchyme | 9.13E-23 | 2.4 |
| Igf1 | Mesenchyme | 2.17E-22 | 2.4 |
| Mbp | Mesenchyme | 1.24E-05 | 2.4 |
| Nts | Mesenchyme | 4.03E-21 | 2.4 |
| Col1a2 | Mesenchyme | 2.15E-20 | 2.3 |
| Sfrp1 | Mesenchyme | 1.36E-18 | 2.2 |
| Acta2 | Mesenchyme | 1.73E-17 | 2.2 |
| Alx1 | Mesenchyme | 1.73E-18 | 2.2 |
| Ccl12 | Leukocyte | 1.64E-09 | 8.0 |
| Cd209f | Leukocyte | 5.12E-06 | 7.5 |
| Cd209g | Leukocyte | 1.36E-04 | 7.3 |
| Mrc1 | Leukocyte | 2.15E-15 | 7.1 |
| Clec10a | Leukocyte | 8.61E-12 | 7.1 |
| Cd86 | Leukocyte | 5.55E-14 | 6.9 |
| Ms4a6c | Leukocyte | 5.11E-20 | 6.8 |
| Ly86 | Leukocyte | 1.11E-13 | 6.8 |
| C1qc | Leukocyte | 9.38E-21 | 6.7 |
| Adgre1 | Leukocyte | 8.73E-15 | 6.7 |
| Ms4a6d | Leukocyte | 1.20E-15 | 6.7 |
| Ccl4 | Leukocyte | 6.94E-10 | 6.7 |
| Ccl3 | Leukocyte | 3.24E-12 | 6.6 |
| Cx3cr1 | Leukocyte | 3.57E-17 | 6.6 |
| Ms4a7 | Leukocyte | 3.20E-18 | 6.6 |
| Fcrls | Leukocyte | 6.42E-15 | 6.6 |
| Ms4a6b | Leukocyte | 2.86E-15 | 6.5 |
| Fcgr3 | Leukocyte | 2.49E-16 | 6.5 |
| Clec4n | Leukocyte | 6.42E-15 | 6.4 |
| Cdh5 | Endothelial cell | 2.54E-58 | 5.2 |
| Lmo2 | Endothelial cell | 3.94E-45 | 5.1 |
| Ccl21a | Endothelial cell | 2.01E-10 | 5.1 |
| Flt1 | Endothelial cell | 3.58E-51 | 5.0 |
| Pecam1 | Endothelial cell | 1.93E-48 | 4.8 |
| Slco2a1 | Endothelial cell | 2.02E-38 | 4.8 |
| Myct1 | Endothelial cell | 1.51E-44 | 4.7 |
| Clec14a | Endothelial cell | 2.91E-43 | 4.7 |
| Kdr | Endothelial cell | 3.94E-45 | 4.7 |
| Plvap | Endothelial cell | 3.21E-43 | 4.6 |
| Cd34 | Endothelial cell | 2.94E-44 | 4.6 |
| Adgrf5 | Endothelial cell | 5.11E-41 | 4.5 |
| Cd93 | Endothelial cell | 1.52E-42 | 4.5 |
| Fabp4 | Endothelial cell | 1.15E-24 | 4.5 |
| Apold1 | Endothelial cell | 4.24E-40 | 4.4 |
| Aplnr | Endothelial cell | 3.11E-38 | 4.4 |
| Emcn | Endothelial cell | 2.05E-40 | 4.4 |
| Cldn5 | Endothelial cell | 2.93E-37 | 4.4 |
| Rgcc | Endothelial cell | 1.26E-37 | 4.3 |