Skip to main content
. 2020 Sep 14;10:15035. doi: 10.1038/s41598-020-70498-w

Table 2.

Transmission disequilibrium test for PLG variants in 314 US trios.

Variant White Hispanic Black Mixed/Other Transmitted Non-transmitted TDT p
p.Lys38Glu 232 44 21 17 3 4 0.71
p.Arg261His 30 3 0 7 0 0 –
p.Ala494Val 49 7 2 9 0 1 0.31
p.Ile682Asn 190 41 22 10 1 0 0.32
p.Asp472Asn 221 44 23 17 101 116 0.31
All variants1 215 43 21 17 104 119 0.32

1For UTMB59, the father transmitted the minor allele for both c.112A > G (p.Lys38Glu) and c.1414G > A (p.Asp472Asn) variants to the child. On the other hand, for each of two trios UTMB132 and UTMB206 one parent carried both c.112A > G (p.Lys38Glu) and c.1414G > A (p.Asp472Asn) variants but did not transmit the minor alleles to the child.