Table 2.
Causal association between prediabetes only and risk of T2D.
| Method | OR | Lower 95% CI | Upper 95% CI | P value |
|---|---|---|---|---|
| Weighted median | 0.98 | 0.82 | 1.14 | 0.79 |
| IVW | 1.02 | 0.90 | 1.16 | 0.76 |
| Robust IVW | 1.02 | 0.90 | 1.15 | 0.77 |
| MR-Egger | 0.91 | 0.73 | 1.14 | 0.42 |
| InterceptMR-Egger | 1.00 | 1.00 | 1.01 | 0.23 |
| Robust MR-Egger | 0.91 | 0.77 | 1.07 | 0.25 |
| InterceptRobust MR-Egger | 1.00 | 1.00 | 1.01 | 0.15 |
n = 28 SNPs. Results are from two-sample Mendelian randomization analyses and P values are two-sided. Results are unadjusted for multiple comparisons. Source data are provided as Source Data file.
IVW inverse-variance weighted, OR odds ratio.