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. 2020 Sep 3;13:8813–8823. doi: 10.2147/OTT.S262359

Figure 2.

Figure 2

Effect of DHT on the growth and viability of human GBM cells. The number of U87 and U251 human GBM cells were counted for 5 days. (A) Effect of DHT on the number of U87 and (C) U251 cells. (B) and (D) Show the effect of DHT on cell viability. Testosterone (T, 100 nM), dihydrotestosterone (DHT, 10 nM), finasteride (FIN, 5 µM), dutasteride (D, 2.5 µM), vehicle (V; 0.01% ethanol). Each point represents the mean ± SD, n = 4. #p<0.05 DHT vs V; &p<0.05 T vs. D; &&&p<0.001 T vs. V; *p<0.05 D vs. V; **p<0.01 DHT vs FIN and FIN+T; ***p<0.001 DHT vs V, D and D+T;+ p<0.05 T vs D and DHT; ++p<0.01 T vs V, FIN and FIN+T; +++p<0.001 T vs D and D+T; @ p<0.05 D vs V.