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. 2020 Sep 3;13:8813–8823. doi: 10.2147/OTT.S262359

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© 2020 Rodríguez-Lozano et al.

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Effect of DHT on GBM cell invasion. (A) Representative photographs are observed in an invasion assay at 24 hours with different treatments in U87 cells. (B) Graphs of U87, and (C) U251 cells represent number of invading cells t at 24 hours with vehicle, testosterone (T, 100 nM), DHT (10 nM), Finasteride (FIN, 5 μM), FIN+ T, Dutasteride (D, 2.5 μM) and D + T, each point represents the mean ± SD, n = 3. +p<0.05 T vs V, and D; ++p<0.01 T vs FIN, DHT vs D, FIN+T and D+T; +++p<0.001 DHT vs V, FIN; * p<0.05 DHT vs FIN+ T; **p<0.01 T vs V, FIN, D+ T, and DHT vs D; ***p<0.001 DHT vs V, FIN, and D+T.