Table 2.

Implant specifications and recorded ion and outcome measurements.

Study ID	Femoral Head Specifications	Serum Concentrations Recorded	Patient Recorded Outcomes
Matsen Ko et al., 2016	Ceramic femoral head	Cobalt, chromium	Oxford Score
	Cobalt chromium femoral head
Nam et al., 2019	Cobalt alloy	Cobalt, chromium, titanium	UCLA Activity Score
	Ceramic femoral head		Harris Hip Score
Chalmers et al., 2019	Ceramic femoral head	Cobalt, chromium	Harris Hip Score
Markel et al., 2019 (HIP International)	Ceramic femoral head	Cobalt, chromium, CD14+ leukocyte, CD16+ leukocyte, CD3+ T lymphocytes, CD19+ B lymphocytes, CD4+ Helper T-cells, CD45 + RA memory vs. naïve T-cells	Harris Hip Score
			12-Item Short-Form Health Survey
			Western Ontario and McMaster Universities Arthritis Index
			Visual Analogue Scale for pain
Markel et al., 2019 (Bone and Joint Journal)	Ceramic femoral head	Cobalt, chromium, IL-2, IL-4, IL-5, IL-10, tumor necrosis factor, interferon gamma, CD3+ T lymphocytes expressing CD4 and/or CD45RA, CD19-expressing B lymphocytes, and monocytes expressing CD14 and/or CD16	Harris Hip Score
			12-Item Short-Form Health Survey
			Western Ontario and McMaster Universities Arthritis Index
			Visual Analogue Scale for pain