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. 2020 Sep 8;6(2):433–446. doi: 10.1016/j.bioactmat.2020.08.019

Fig. 5.

Fig. 5

Evaluation of CD44 receptor activation. A, B: Fluorescence was observed by confocal microscopy under different magnifications after cells were treated with siRNA@CS-HAD NPs. The red fluorescence was cy3-siRNA loaded by the nanoparticles, and the green fluorescence was FITC-stained CD44 with antibody. C: The interference effect of the targeted gene, Bcl2, was detected by qPCR. (*p < 0.05, ****p < 0.0001).