Table 2.
Results of meta-analysis comparing coagulopathy in COVID-19 patients with and without severe illness or mortality.
| Coagulation parameters | Mild vs severe |
Non-ICU vs ICU |
Survival vs Non-survival |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #of studies (#of ptsa) | MD (95%CI) | I2 | Cochran’s Q P-value | #of studies (# of ptsa) | MD (95%CI) | I2 | Cochran’s Q P-value | #of studies (# of ptsa) | MD (95%CI) | I2 | Cochran’s Q P-value | |
| PLT(×109/L) | 2 (356) | 16.63 (0.39,32.86) | 0% | 0.04 | 3 (213) | −0.19 (−20.22,19.85) | 0% | 0.99 | 3 (979) | 51.47 (38.41,64.54) | 0% | <0.001 |
| PT(s) | 5 (620) | −0.50 (−0.97,−0.03) | 82% | 0.04 | 4 (325) | 0.54 (0.13,0.95) | 0% | 0.01 | 5 (1307) | −1.10 (−1.37,−0.83) | 38% | <0.001 |
| APTT(s) | 4 (475) | −1.15 (−3.59,1.30) | 75% | 0.36 | 4 (325) | −0.59 (−1.84,0.67) | 0% | 0.36 | 2 (522) | −2.42 (−5.84,1.01) | 70% | 0.17 |
| D-D(mg/L) | 7 (790) | −0.83 (−1.31,−0.34) | 84% | <0.001 | 3 (213) | 3.51 (−7.40,14.41) | 85% | 0.53 | 5 (1307) | −6.01 (−8.99,−3.03) | 81% | <0.001 |
| FIB(g/L) | 2 (119) | −0.76 (−1.20,−0.32) | 0% | <0.001 | – | – | – | – | – | – | – | – |
–, Not available, not reported.
a
pts: patients.