Table 3.
Summary of average daily total nasal symptom score and daily rescue medication scores during peak pollen period.
| FAS population |
PPS population |
|||
|---|---|---|---|---|
| SLIT | Placebo | SLIT | Placebo | |
| N | 421 | 211 | 395 | 195 |
| Daily total nasal symptom score | ||||
| Mean ± SD | 3.84 ± 1.06 | 4.74 ± 0.98 | 3.79 ± 1.08 | 4.88 ± 1.01 |
| P value | <0.0001 | <0.001 | ||
| Improvement | 19.0% | 22.3% | ||
| Adjusted mean difference (95% CI) | 0.663 (0.447–0.879) | 0.883 (0.672–1.094) | ||
| Daily rescue medication scores | ||||
| Mean ± SD | 0.56 ± 0.27 | 0.71 ± 0.26 | 0.54 ± 0.29 | 0.73 ± 0.27 |
| P value | <0.0001 | <0.0001 | ||
| Improvement | 22.0% | 26.0% | ||
| Adjusted mean difference (95% CI) | 0.154 (0.101–0.206) | 0.131 (0.088–0.175) | ||
FAS, full analysis set; PPS, per protocol set; SLIT, sublingual immunotherapy; CI, confidence intervals