Table 2.
Label-free G4-based fluorescence OTA detection methods.
| Aptamer (5′-3′) | Probe | LOD | References |
|---|---|---|---|
| d(GATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACA) | TMPyP | 0.16 ng/mL | Liu et al., 2019 |
| d(GATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACA) | DSAI | 1.9 ng/mL | Lv et al., 2019 |
| d(TGGGTAGGGCGGGTTGGGAAAGATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACA) | / | 4 nM | Yang et al., 2013 |
| d(GATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACA) | Iridium complex | 10.8 nM | Zhang J.-T. et al., 2019 |
| d(GATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACA) | Protoporphyrin IX zinc(II) | 0.03 nM | Liu F. et al., 2018 |
| d(GATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACATTTTTT) | N-methylmesoporphyrin IX | 0.0002 ng/mL | Wang J. et al., 2019 |
| d(GATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACA) | Thioflavin T | 0.4 ng/mL | Wu et al., 2018 |
| d(GATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACA) | / | 2 ng/mL | Armstrong-Price et al., 2020 |
| d(CCGCCCGATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACACCCGCC) | d(GGGTAGGGCGGGTTGGG) | 0.07 ng/mL | Wang Y. et al., 2019 |
| d(GATCGGGTGTGGGTGGCGTAAAGGGAGCATC) | Coumarin–hemicyanine hybrid and 4-quinolinium-indole | 6 ng/mL | Deore et al., 2019 |
| Thioflavin T | 29 ng/mL | ||
| d(GATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACA) | Thioflavin T | 0.38 ng/mL | Zeng et al., 2019 |
| d(GATCGGGTGTGGGTGGCGTAAAGGGAGCATCGGACACGCCACCCACAC) | Hairpin 1 and 2 | 4.9 Pm | Qian et al., 2020 |