Table 1.
Sex | Metal | Dose | Water Intakeb | Body Wt. (g) | Small Intestine Length (cm) | # of Peyer’s Patches |
---|---|---|---|---|---|---|
Male | U | Control | 4.10 ± 0.34 | 30.68 ± 1.36 | 34.43 ± 1.82 | 7.50 ± 1.52 |
5 ppm | 4.39 ± 0.71 | 30.63 ± 1.93 | 34.48 ± 2.16 | 6.17 ± 0.75 | ||
50 ppm | 3.92 ± 0.40 | 30.49 ± 1.06 | 34.42 ± 0.97 | 6.50 ± 2.07 | ||
As3+ | Control | 3.07 ± 0.25 | 33.36 ± 3.16 | 35.83 ± 1.44 | 5.00 ± 1.10 | |
100 ppb | 3.31 ± 0.31 | 31.07 ± 1.60 | 34.83 ± 1.86 | 6.17 ± 1.60 | ||
500 ppb | 3.24 ± 0.26 | 29.26 ± 3.26 | 35.73 ± 1.19 | 5.83 ± 0.75 | ||
Female | U | Control | 3.22 ± 0.54 | 22.40 ± 0.80 | 32.68 ± 0.68 | 6.33 ± 1.34 |
5 ppm | 3.16 ± 0.27 | 23.90 ± 1.34 | 34.17 ± 1.65 | 6.17 ± 1.47 | ||
50 ppm | 3.17 ± 0.35 | 22.58 ± 2.15 | 32.23 ± 2.31 | 6.67 ± 0.82 | ||
As3+ | Control | 2.72 ± 0.21 | 24.80 ± 2.85 | 35.63 ± 2.62 | 7.50 ± 0.84 | |
100 ppb | 2.52 ± 0.33 | 25.21 ± 1.80 | 35.70 ± 1.85 | 6.00 ± 1.55 | ||
500 ppb | 2.31 ± 0.20 | 23.53 ± 2.14 | 34.82 ± 1.15 | 7.17 ± 0.98 |
Water intake = mL of water consumed per mouse per day.
Data expressed as mean ± SD of each group (n = 5).