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. Author manuscript; available in PMC: 2020 Dec 15.
Published in final edited form as: Toxicol Lett. 2019 Sep 25;317:1–12. doi: 10.1016/j.toxlet.2019.09.013

Table 1.

Linear regression slopes (with standard errors) of the all variable investigated following exposure to PC and ABS 3-D printer-emitted particles collected in the cell culture medium. All statistical analyses were performed in either SAS v9.4, or JMP v13. Mixed model regression analyses were performed on the measured variables using particle number*10−4 as the independent variable, and printer batch as a random factor. Regressions coefficients which are significantly different from 0, indicate dose-responsiveness of the dependent variables. Analyses were performed for the two filaments separately. All analyses are considered significant at p < 0.05 (*).

Variable PC ABS
Slope StdErr Slope StdErr
Viability, % of Control −0.04790* 0.00319 − 0.04794* 0.00733
LDH, % of Control 0.05077* 0.00636 0.11021* 0.00852
ROS, % of Control 0.07479* 0.00960 0.14836* 0.01950
TAC, % of Control −0.00657* 0.00233 − 0.03915* 0.00847
GPx, % of Control −0.01604* 0.00133 − 0.03511* 0.00690
Apoptosis, % of Control 0.28506* 0.05598 0.37508* 0.05277
Necrosis, % of Control 0.23467* 0.03618 0.14447* 0.03246
IL-12p70, pg/total cells 0.00650* 0.00111 0.00760* 0.00112
IL-13, pg/total cells 0.00020* 0.00004 0.00022* 0.00003
IL-16, pg/total cells 0.12797* 0.02741 0.09414* 0.00960
IL-1β, pg/total cells 0.09851* 0.03645 0.00125* 0.00017
IL-1α, pg/total cells 0.01725* 0.00543 0.00268* 0.00081
IL-6, pg/total cells 0.00001* 0.00000 0.00002* 0.00000
IL-8, pg/total cells 0.00095* 0.00018 0.00005 0.00015
TNF-α, pg/total cells 0.00619* 0.00119 0.00064 0.00038