Table 3:
Receipt of Individual Procedures (Secondary Outcomes) within 30 Days After Acute Ischemic Stroke Between Participants with Pre-existing Mild Cognitive Impairment and Cognitively Normal Patients
Receipt of individual procedures (secondary outcomes) | Participants with Normal Cognition (n=432) | Participants with Pre-existing MCI (n=159) | P-value* | Unadjusted odds ratios (95% CI) for MCI vs normal cognition | Adjusted odds ratios (95% CI) for MCI vs normal cognition |
---|---|---|---|---|---|
Carotid imaging | 342 (79.2) | 118 (74.2) | 0.20 | 0.76 (0.50–1.16) P=0.20 |
0.93 (0.58–1.51) P=0.78 |
Cardiac monitoring | 24 (5.6) | 3 (1.9) | 0.06 | 0.33 (0.10–1.10) P=0.07 |
NA |
Echocardiogram | 332 (76.9) | 113 (71.1) | 0.15 | 0.74 (0.49–1.11) P=0.15 |
0.93 (0.58–1.50) P=0.77 |
Brain MRI | 247 (57.2) | 83 (52.2) | 0.28 | 0.82 (0.57–1.18) P=0.28 |
1.13 (0.74–1.74) P=0.56 |
Rehabilitation assessment | 46 (10.7) | 10 (6.3) | 0.11 | 0.56 (0.28–1.14) P=0.11 |
NA |
Carotid revascularization** | 22 (5.1) | 3 (1.9) | 0.09 | 0.36 (0.11–1.21) P=0.10 |
NA |
Composite brain imaging measure | |||||
None | 45 (10.4) | 14 (8.8) | 0.38 | Referent | Referent |
Head CT only | 140 (32.4) | 62 (39.0) | 1.42 (0.73–2.78) P=0.30 |
1.13 (0.52–0.47) P=0.75 |
|
Brain MRI only | 53 (12.3) | 14 (8.8) | 0.85 (0.37–1.97) P=0.70 |
0.77 (0.29–2.06) P=0.61 |
|
Dual brain imaging with CT and MRI | 194 (44.9) | 69 (43.4) | 1.14 (0.59–2.21) P=0.69 |
1.39 (0.64–3.00) P=0.40 |
Abbreviations: MCI, mild cognitive impairment. CT, computed tomography. MRI, magnetic resonance imaging. NA, not applicable.
P-values were calculated using chi square test for categorical variables.
Carotid revascularization measured within 90 days after acute ischemic stroke. Carotid imaging included ultrasound, magnetic resonance angiography, or computerized tomography angiography. Cardiac monitoring included cardiac event monitor or implantable loop recorder. Echocardiogram include transthoracic and transesophageal echocardiogram. Logistic regression models estimated the odds of receiving the individual procedures (secondary outcomes) before and after adjusting for patient and hospital factors.
Adjusted models included patient factors (age, sex, race/ethnicity, education, net wealth, income, Charlson comorbidity index score, depressive symptoms, functional limitations in basic and instrumental activities of daily living, marital status/living arrangement, geographic proximity to adult children, and having an adult daughter) and hospital factors (medical school affiliate or teaching hospital, region, bed size, and authority type).
We do not present adjusted results for these individual procedures because numbers are small.