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. 2020 Sep 9;20(5):70. doi: 10.3892/etm.2020.9198

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Copyright: © Fu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of CGA on the insulin content and PI3K/AKT protein expression levels in the hippocampus of rats with MID. (A) Concentration of insulin. Levels of p-PI3K, PI3K, p-AKT and AKT protein expression were (B) determined by western blot analysis and the ratio of (C) p-PI3K/PI3K and (D) p-AKT/AKT were quantified. ^*P<0.05 and ^**P<0.01 vs. the sham group; ^#P<0.05, ^##P<0.01 and ^#^##P<0.001 vs. the model group. CGA, compatibility of ginsenosides and astragalosides; MID, multi-infarct dementia; p, phosphorylated; CGA H, high-dose CGA; CGA L, low-dose CGA.