Table 3:

Association between variables and 6- and 12-month Persistent Respiratory Morbidity (PRM)

	At 6 months			At 12 months
Variable	No PRM (n = 92)	PRM (n = 66)	p value	No PRM (n = 72)	PRM (n = 58)	p value
Demographics
Age (months)	1.5 (1, 2.25)	2 (1, 6)	0.031	1.25 (1, 2.25)	2 (1, 4)	0.048
Female (%)	30 (33)	25 (38)	0.503	25 (34)	20 (35)	1
Non-white race (%)	15 (16)	17 (26)	0.163	9 (12)	13 (23)	0.157
Hispanic (%)	12 (13)	13 (20)	0.376	9 (12)	9 (16)	0.795
Admission diagnosis (%)
RSV bronchiolitis	53 (58)	36 (55)	0.387	40 (55)	32 (56)	0.758
Other bronchiolitis	17 (19)	10 (15)		15 (19)	11 (19)
Other pneumonia	8 (9)	11 (17)		5 (7)	7 (12)
Other resp failure	11 (12)	9 (14		12 (16)	6 (11)
Non-pulmonary	3 (3)	0		2 (3)	1 (2)
PRISM III score	4 (2, 6)	3.5 (3, 6)	0.53	5 (2, 6)	4 (2, 8)	0.86
Worst OIa	5.9 (3.4, 8.8)	9.5(5.2, 15.8)	0.006	6.4 (3.8, 15.7)	7.5 (3.5, 12.9)	0.71
Highest ventilator parameters
PIP (cmH2O)	31 (28, 35)	31.5 (28, 36)	0.53	31 (28, 35.5)	30.5 (27, 35)	0.68
PEEP (cmH2O)	5 (5, 7.5)	6 (5, 8)	0.18	5 (5, 7)	5 (5, 6.9)	0.16
First Three-day average ventilator parameters
PIP (cmH2O)	27 (22.7, 31.5)	27.3 (25, 31.3)	0.64	27 (23, 31.7)	26.2 (22.7, 30.7)	0.38
PEEP (cmH2O)	5 (5, 6)	5 (5, 6.3)	0.18	5 (5, 5.7)	5 (5, 6.9)	0.16
Specific virus positive (%)
RSV	54 (73)	36 (63)	0.258	46 (75)	32 (67)	0.393
Influenza	1 (1)	1 (2)	1	1 (2)	2 (4)	0.582
Parainfluenza	2 (3)	2 (4)	1	2 (3)	0	0.503
Adenovirus	0	0	-	0	0	-
Bacterial culture pos (%)	40 (54)	42 (72)	0.046	27 (44)	36 (75)	0.002
Duration of support
Ventilator days	5 (4, 8)	6 (4, 10)	0.52	5 (4, 7.5)	5 (4, 9)	0.68
Oxygen days	9 (6, 12)	9.5 (7, 13)	0.39	9 (6.5, 12)	9 (6, 13)	0.85
PICU days Mortality (%)	7 (5, 10.5)	8 (6, 13)	0.11	7 (5, 11)	8 (6, 12)	0.42
PDAD at discharge (%)	19 (21)	31 (47)	<0.001	19 (26)	21 (36)	0.250
PRM at 6 months (%)	-	-	-	10 (14)	41 (73)	<0.001

^aOSI is converted to OI