Table 2:
Cost Component | Prevalent treated CD (2014) | Prevalent treated UC (2014) | ||||||
---|---|---|---|---|---|---|---|---|
18-64 years (n=7,663) | ≥ 65 years (n=2,454) | 18-64 years (n=14,631) | ≥ 65 years (n=5,131) | |||||
Resource use | Mean cost (SD) | Resource use | Mean cost (SD) | Resource use | Mean cost (SD) | Resource use | Mean cost (SD) | |
Variable | ||||||||
Drug use, % of patients | ||||||||
Biologic drug use | ||||||||
Anti-TNF with approved indication in IBD | 21.9% | 4,444 (10,001) | 6.8% | 1,386 (5,762) | 7.4% | 1,456 (6,074) | 2.4% | 435 (3,173) |
Other biologics | 0.4% | 50 (924) | 0.2% | 20 (593) | 0.1% | 15 (510) | 0.0% | 1 (84) |
Total biologic drug use | 22.2% | 4,495 (10,029) | 6.9% | 1,407 (5,807) | 7.4% | 1,471 (6,095) | 2.4% | 436 (3,175) |
Other non-biologic drug use | ||||||||
Immunomodulators | 50.8% | 181 (413) | 30.3% | 101 (316) | 25.2% | 96 (325) | 14.9% | 58 (275) |
5-aminosalicylic acid | 26.9% | 200 (406) | 29.5% | 225 (422) | 70.1% | 598 (645) | 63.1% | 501 (573) |
Corticosteroids | 33.4% | 114 (350) | 48.1% | 209 (438) | 25.0% | 27 (141) | 34.3% | 44 (172) |
Other drugs | 90.3% | 889 (5,076) | 98.6% | 1,365 (3,127) | 85.9% | 679 (2,459) | 97.2% | 1,321 (5,971) |
Total drug use | 97.9% | 5,830 (11,131) | 99.1% | 3,288 (6,524) | 97.2% | 2,858 (6,622) | 99.2% | 2,361 (6,806) |
Hospital care, mean (std) | ||||||||
Non-primary outpatient care visits | 3.9 (5.6) | 1,926 (3,133) | 4.4 (4.9) | 2,092 (2,515) | 2.9 (4.4) | 1,447 (2,341) | 3.5 (5.0) | 1,706 (2,640) |
Gastroenterologist/internist | 1.8 (3.2) | 913 (1,912) | 1.4 (2.1) | 720 (1,210) | 1.3 (2.7) | 654 (1,523) | 1.0 (1.7) | 538 (1,006) |
Other specialists | 2.1 (4.3) | 1,013 (2,352) | 2.9 (4.2) | 1,371 (2,084) | 1.6 (3.3) | 792 (1,674) | 2.5 (4.5) | 1,168 (2,378) |
Inpatient days | 1.9 (9.4) | 2,338 (8,233) | 4.0 (11.9) | 4,346 (11,112 | 1.2 (7.2) | 1,619 (7,610 | 3.5 (10.7) | 4,004 (11,378 |
Bowel surgery | 0.3 (2.7) | 479 (2,980) | 0.3 (2.8) | 381 (3,517) | 0.1 (1.5) | 220 (2,163) | 0.2 (2.2) | 288 (3,301) |
Total hospital care | 4,265 (9,796) | 6,438 (12,025) | 3,067 (8,614) | 5,711 (12,230) | ||||
Total healthcare cost | 10,096 (15,442) | 9,726 (14,161) | 5,926 (11,480) | 8,072 (14,338) | ||||
Work loss | ||||||||
Sick leave, n days | 19.3 (62.4) | 3,900 (12,571) | 15.5 (54.6) | 3,118 (11,015) | ||||
Disability pension, n days | 43.7 (110.3) | 8,816 (22,235) | 25.3 (86.4) | 5,091 (17,416) | ||||
Total work loss, n days | 63.1 (122.0) | 12,717 (24,602) | 40.7 (100.2) | 8,209 (20,196) | ||||
Societal cost | 22,813 (31,454) | 9,726 (14,161) | 14,136 (25,684) | 8,072 (14,338) |