Table 3:
Cost Component | Incident treated CD (2010-2013) | Incident treated UC (2010-2013) | ||||||
---|---|---|---|---|---|---|---|---|
18-64 years (n=3,201) | ≥ 65 years (n=827) | 18-64 years (n=6,736) | ≥ 65 years (n=1,923) | |||||
Resource use | Mean cost (SD) | Resource use | Mean cost (SD) | Resource use | Mean cost (SD) | Resource use | Mean cost (SD) | |
Variable | ||||||||
Drug use, % of patients | ||||||||
Biologic drug use | ||||||||
Anti-TNF with approved indication in IBD | 12.8% | 2,289 (7,024) | 4.2% | 746 (3,959) | 5.0% | 830 (4,491) | 1.4% | 215 (2,266) |
Other biologics | 0.1% | 11 (441) | 0.2% | 12 (262) | 0.0% | 1 (54) | 0.1% | 10 (473) |
Total biologic drug use | 12.9% | 2,301 (7,045) | 4.2% | 759 (4,029) | 5.0% | 831 (4,493) | 1.5% | 226 (2,314) |
Other non-biologic drug use | ||||||||
Immunomodulators | 45.7% | 99 (261) | 26.1% | 49 (181) | 18.8% | 37 (152) | 10.7% | 19 (116) |
5-aminosalicylic acid | 40.0% | 325 (563) | 30.4% | 241 (485) | 90.3% | 834 (766) | 73.4% | 618 (700) |
Corticosteroids | 83.6% | 324 (507) | 87.4% | 361 (553) | 54.9% | 74 (199) | 66.0% | 119 (296) |
Other drugs | 94.6% | 797 (2,176) | 99.6% | 1,611 (3,106) | 90.2% | 733 (2,423) | 98.5% | 1,261 (2,258) |
Total drug use | 100.0% | 3,837 (7,342) | 100.0% | 3,010 (5,059) | 100.0% | 2,509 (5,252) | 100.0% | 2,234 (3,361) |
Hospital care, mean (std) | ||||||||
Non-primary outpatient care visits | 5.7 (5.8) | 2,794 (3,006) | 6.1 (8.4) | 2,905 (4,347) | 4.3 (4.4) | 2,212 (2,310) | 4.8 (5.9) | 2,400 (3,216) |
Gastroenterologist/internist | 3.2 (3.3) | 1,548 (1,651) | 2.6 (3.3) | 1,229 (1,637) | 2.4 (2.8) | 1,244 (1,551) | 2.0 (2.4) | 1,021 (1,352) |
Other specialists | 2.5 (4.7) | 1,246 (2,472) | 3.5 (7.7) | 1,676 (4,031) | 1.9 (3.2) | 967 (1,694) | 2.8 (5.3) | 1,378 (2,912) |
Inpatient days | 3.4 (9.9) | 5,152 (10,597 | 8.8 (18.4) | 10,367 (21,437 | 2.4 (9.2) | 3,204 (9,324 | 7.0 (16.6) | 7,556 (14,654 |
Bowel surgery | 0.6 (3.2) | 1,093 (4,530) | 0.8 (3.9) | 1,225 (5,110) | 0.2 (2.1) | 392 (2,885) | 0.6 (4.1) | 901 (5,348) |
Total hospital care | 7,946 (11,931) | 13,272 (22,689) | 5,416 (10,429) | 9,956 (15,654) | ||||
Healthcare cost | 11,784 (14,678) | 16,282 (23,645) | 7,926 (12,691) | 12,191 (16,485) | ||||
Work loss | ||||||||
Sick leave, n days | 29.1 (73.8) | 5,858 (14,882) | 20.2 (58.3) | 4,073 (11,756) | ||||
Disability pension, n days | 31.0 (96.5) | 6,243 (19,448) | 23.7 (84.8) | 4,778 (17,087) | ||||
Total work loss, n days | 60.0 (115.5) | 12,102 (23,277) | 43.9 (99.9) | 8,852 (20,137) | ||||
Societal cost | 23,886 (30,797) | 16,282 (23,645) | 16,778 (27,043) | 12,191 (16,485) |