Table 4.
Fully adjusted HR of risk factors for cardiac-specific mortality according to the presence of NAFLD (multiple-imputation analysis).
| Covariate | Individuals with NAFLD |
Individuals without NAFLD |
||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Sarcopenia | 3.19 (1.17–8.74) | 0.0239 | 2.37 (0.94–5.99) | 0.068 |
| Age (years) | ||||
| 20–39 | Reference | Reference | ||
| 40–59 | 0.62 (0.14–2.78) | 0.5289 | 0.39 (0.06–2.52) | 0.325 |
| >60 | 2.86 (1.22–6.70) | 0.0153 | 2.49 (1.20–5.17) | 0.0142 |
| Male | 3.32 (1.11–9.91) | 0.0312 | 3.30 (1.61–6.76) | 0.0011 |
| Race | ||||
| Non-Hispanic White | Reference | Reference | ||
| Non-Hispanic Black | 2.04 (0.86–4.86) | 0.1060 | 0.53 (0.23–1.18) | 0.1205 |
| Hispanic | 1.57 (0.53–4.63) | 0.4125 | 0.44 (0.13–1.52) | 0.1955 |
| Other race | N/A | 0.17 (0.02–1.54) | 0.1156 | |
| Low income | 0.69 (0.26–1.81) | 0.45 | 2.31 (1.33–4.01) | 0.0031 |
| College | 0.88 (0.36–2.14) | 0.7833 | 0.39 (0.14–1.12) | 0.0812 |
| Height (cm) | 1.00 (0.96–1.05) | 0.8556 | 0.98 (0.94–1.02) | 0.3903 |
| Physical inactivity | 1.15 (0.50–2.69) | 0.7401 | 1.29 (0.64–2.58) | 0.4784 |
| Active smoker | 2.04 (0.94–4.45) | 0.0726 | 0.62 (0.25–1.52) | 0.2931 |
| Hypertension | 1.44 (0.52–3.96) | 0.4821 | 2.99 (1.29–6.93) | 0.0107 |
| Hyperlipidaemia | 2.00 (0.59–6.82) | 0.2691 | 1.15 (0.47–2.84) | 0.7562 |
| Diabetes | 3.06 (1.26–7.42) | 0.0133 | 3.93 (1.83–8.47) | 0.0005 |
| History of cancer | 4.42 (2.20–8.89) | <0.0001 | 3.18 (1.48–6.84) | 0.0031 |
| History of CVD | 1.81 (0.77–4.27) | 0.1765 | 1.30 (0.59–2.85) | 0.5115 |
| History of kidney disease | 3.21 (0.78–13.24) | 0.1058 | 3.65 (1.18–11.34) | 0.0249 |
CVD, cardiovascular disease; HR, hazard ratio; NAFLD, non-alcoholic fatty liver disease.