Table 5.
Fully adjusted HR of risk factors for cancer-specific mortality according to the presence of NAFLD (multiple-imputation analysis).
| Covariate | Individuals with NAFLD |
Individuals without NAFLD |
||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Sarcopenia | 2.12 (1.08–4.15) | 0.0293 | 1.68 (0.59–4.80) | 0.3299 |
| Age (years) | ||||
| 20–39 | Reference | Reference | ||
| 40–59 | 0.36 (0.08–1.68) | 0.1948 | 0.57 (0.27–1.23) | 0.1534 |
| >60 | 3.43 (1.78–6.60) | 0.0002 | 1.70 (0.82–3.53) | 0.153 |
| Male | 2.20 (0.92–5.24) | 0.0747 | 1.96 (0.94–4.06) | 0.071 |
| Race | ||||
| Non-Hispanic White | Reference | Reference | ||
| Non-Hispanic Black | 1.17 (0.34–4.06) | 0.8008 | 3.08 (1.70–5.56) | 0.0002 |
| Hispanic | 0.45 (0.24–0.87) | 0.0164 | 1.51 (0.60–3.80) | 0.3864 |
| Other race | 0.18 (0.02–1.61) | 0.1254 | 1.76 (0.49–6.33) | 0.3882 |
| Low income | 1.35 (0.64–2.86) | 0.4376 | 1.14 (0.61–2.13) | 0.6716 |
| College | 0.55 (0.20–1.52) | 0.2508 | 0.80 (0.37–1.74) | 0.5751 |
| Height (cm) | 0.99 (0.96–1.02) | 0.4819 | 1.00 (0.96–1.03) | 0.8443 |
| Physical inactivity | 0.93 (0.49–1.78) | 0.8301 | 0.75 (0.42–1.34) | 0.3397 |
| Active smoker | 1.87 (0.94–3.73) | 0.0738 | 1.83 (1.18–2.84) | 0.0067 |
| Hypertension | 1.49 (0.77–2.87) | 0.2367 | 1.89 (1.11–3.20) | 0.0181 |
| Hyperlipidaemia | 2.04 (0.82–5.06) | 0.1261 | 1.17 (0.68–1.99) | 0.5724 |
| Diabetes | 1.00 (0.56–1.81) | 0.9913 | 0.83 (0.32–2.18) | 0.7044 |
| History of cancer | 1.91 (1.05–3.46) | 0.0341 | 2.49 (1.18–5.26) | 0.0171 |
| History of CVD | 2.13 (0.99–4.59) | 0.0532 | 6.12 (3.72–10.06) | <0.0001 |
| History of kidney disease | 0.91 (0.18–4.49) | 0.9073 | 1.52 (0.52–4.45) | 0.4475 |
CVD, cardiovascular disease; HR, hazard ratio; NAFLD, non-alcoholic fatty liver disease.