Fig. 6.

Signaling pathway analysis. a Western blot and protein quantification showing the expression of p-ERK, ERK, p-MEK, MEK, and β-actin in kidney tissue. b Western blot and protein quantification showing the expression of p-Akt, Akt, and β-actin in kidney tissue. c Western blot and protein quantification showing the expression of SIRT3, eNOS, and β-actin in kidney tissue. Each group has n = 3 mice. Significant difference ^ap < 0.05: relative to untreated control; ^bp < 0.05: relative to AKI; ^cp < 0.05: relative to AKI-EV; ^dp < 0.05: relative to AKI-EV-pFUS