Table 3.

Best and main model

Biological factors related to hyperglycemia	Threshold	Relevance
Fasting glucose	<132 mg/dL	0.66
A1c reduction speed	>0.38 point HbA1c/year	0.59
Distance from target 7%	≤0.02 point HbA1c	0.59

Biological factors related to insulin resistance	Threshold	Relevance
BP systolic	<134 mm Hg	0.06
Total cholesterol	<185 mg/dL	0.04
Triglycerides	<110 mg/dL	0.09
HDL	>52	0.03

Comorbidity	Condition	Relevance
Nephropathy	Absent	0.02
Albuminuria	Absent	0.02
Retinopathy	Absent	0.02
Liver disease	Absent	0.02

History and care	Threshold or condition	Relevance
Years of observation	<6	0.12
Months of follow-up	<19	0.09
Interval between visits (Years)	<0.9	0.30
Q Score	>29	0.10
Sex	Male	0.03

Diabetes therapy	Condition	Relevance
Insulin alone or in addition to oral agents	Absent	0.32

The model identifies the following factors as relevant for achieving the target: AUC 0.74, accuracy 0.75, sensitivity 0.74, specificity 0.74, precision 0.72. NPV 0.76.

AUC, area under the curve; BP, blood pressure; HDL, high density lipoprotein; NPV, negative predictive value.