Table 4.

Only Hba1c model

Biological factors related to hyperglycemia	Threshold	Relevance
Fasting glucose	<118–133 mg/dL	0.66
A1c reduction speed	>−0.10 point HbA1c/year	0.59
Distance from target 7%	<0.7–0.9 point HbA1c	0.59

Biological factors related to insulin resistance	Threshold	Relevance
BP systolic	<115–125 mm Hg	0.04
Total cholesterol	<189 mg/dL	0.01
Triglycerides	<125–130 mg/dL	0.08
HDL	>47	0.04

Comorbidity	Condition	Relevance
Nephropathy	Absent	0.03
Albuminuria	Absent	0.03
Retinopathy	Absent	0.03
Liver disease	Absent	0.03

History and care	Threshold or condition	Relevance
Years of observation	<5	0.16
Months of follow-up	<0,9	0.28
Q Score	>27–30	0.10
Sex	Male	0.03

Diabetes therapy	Condition	Relevance
Insulin alone	Present	0.73
Any oral agents	Present	0.73

The model identifies the following factors as relevant for achieving the target: AUC 0.74, accuracy 0.74, sensitivity 0.74, specificity 0.74, precision 0.72, NPV 0.76.

AUC, area under the curve; BP, blood pressure; HDL, high density lipoprotein; NPV, negative predictive value.