Table 1.
Summary of reports on extra-articular synovial osteochondromatosis [13].
| S No | Author/year | Age/Gender | Presentation | Radiology | Treatment | Biopsy |
|---|---|---|---|---|---|---|
| 1 | Franklin et al./1977 | 45/F | Recurrent swelling in anterior aspect of ankle | Radiograph - Irregularity in cortex of distal end of tibia and soft tissue swelling with calcification | Open exploration and excision | Lobules of cartilage within synovial tissue without bony invasion |
| 2 | Thomas et al./1980 | 47/F | Recurrent mass on the anterior aspect of the ankle | Radiograph - Soft tissue mass on anterior part of tibia with irregular margin and destruction of anterior cortex; Recurrence after 2 years - X ray revealed extensive lesion involving the anterior aspect of distal end tibia with intra - medullary extension | Subtotal excision biopsy Recurrence: B/K amputation | Initial HPE - Lobules of cartilage cells with intervening acellular stroma; HPE of recurrence - Two distinct patterns: 1) chondrocyte cluster with intervening acellular stroma, 2) sheets of cartilage cells with moderately atypical nuclei |
| 3 | Tibrewal et al./1995 | 44/F | Painful soft tissue mass over anterolateral aspect of right ankle | Radiograph - Lytic area in the lower tibia & fibula with scalloping of margin, extending to articular surface, soft tissue mass around ankle without calcification; CT - Well defined soft tissue mass with calcification and erosion of tibiofibular syndesmosis | Open excision | Lobules of cartilage with covering of hyaline material and synovium along with focal osteoid formation, some enlarged chondrocyte nuclei without atypia |
| 4 | Van et al./2006 | 56/F | Mass in the posterior aspect of left ankle for 2 years, pain for 6 months and increasing in size for 2 months | Radiograph - soft tissue density with a circumscribed mass posterior to ankle & subtalar joint; MRI - multiple cystic appearing masses along tibiotalar joint extending cephalad along the posterior margin of FHL. Anterior extension to talus through the sinus tarsi, laterally to anterior and medial margin of peroneal tendon, no ossification | Open excision | Chondrocyte metaplasia with cartilaginous nodules within synovial membrane |
| 5 | Kim et al./2013 | 32/M | Painful swelling left subtalar region laterally | Radiograph, CT - huge, rounded, finely stippled, calcified mass with radio-opaque bodies lateral to subtalar joint. MRI - T2 weighted high signal intensity compatible with calcification and ossification with hypointense septa | Open excision | Nodules of mature hyaline cartilage located under a layer of synovial membrane, with central ossification and osteoblastic rimming |
| 6 | Lui et al./2014 | 55/F | Lump over the dorsum of the foot with pain and gradually increasing size | MRI - Cyst around the EDL tendon with multiple calcified masses | EDL tendoscopy with synovectomy, ankle arthroscopy with removal of loose body & debridement | Cartilaginous nodules with inflamed synovial tissue |
| 7 | Nichelle et al./2015 | 17/F | Intermittent swelling and discomfort posterior to left medial malleolus | Radiograph - Soft-tissue density obscuring Kagers fat pad; MRI - distension of FHL tendon sheath with innumerable non ossified cartilage bodies measuring 1−4mm | open excision | Nodules rich in chondroid matrix with reactive chondrocytes |
| 8 | Pinter et al./2017 | 48/M | Painful mass over the posteromedial aspect of right ankle | Radiograph - Mass without calcification; MRI - 4 cm irregular mass involving FDL, FHL and PT | open excision | Cluster of clonal chondrocytes arranged in lobules, with variable atypia and occasional bi nucleation |
| 9 | Isbell et al./2017 | 27/M | Recurrence of progressively increasing left ankle pain and swelling along with tingling and burning in plantar aspect of foot | Radiograph - Opacity over the pre-Achilles fat pad and posterior ankle soft tissue; US - Joint capsule distension with intra articular debris and synovial hyperemia; MRI - Multiple large lobulated heterogeneous lesions with enhancement around FHL tendon extending into anterior tibiotalar joint and minimal involvement of sinus tarsi | Arthroscopic debridement of joint along with open excision | Cartilage hyaline nodules with minimal atypia of the chondrocytes and infrequent mitosis |
| 10 | Dheer et al./2020 | 49/F | Palpable swelling in the lateral aspect of ankle | US - Lobulated heterogeneous lesion with internal echogenicity; Doppler - neo vascularity; MRI - well lobulated mass near the peroneal tendon sheath with nodular and lace-like internal enhancement | Open surgical excision | Lobules of cartilage proliferation, minimal cellularity, no nuclear atypia and low nuclear to cytoplasmic ratio |
Abbreviations: B/K – below knee, CT – computerized tomography, MRI – Magnetic resonance imaging, FHL – Flexor Hallucis Longus, EDL – Extensor Digitorum Longus, FDL – Flexor Digitorum Longus, PT – Tibialis Posterior US- Ultrasonogram, M – Male, F – Female.