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. 2020 Sep 1;11:2089. doi: 10.3389/fmicb.2020.02089

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Copyright © 2020 Shang, Wan, Zhao, Meng and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of Bifidobacterium bifidum H3-R2 administration on the secretion of IL-10 (A), TNF-α (B), and SIgA (C) in mice. NC, normal control group; CM, CTX-induced model group; PC, positive control group; BH, high-dose group of B. bifidum H3-R2; BM, middle-dose group of B. bifidum H3-R2; BL, low-dose group of B. bifidum H3-R2. Values are expressed in mean ± SD (six mice per group). The different letters represent significant differences (P < 0.05).