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. 2020 Sep 8;20(5):209. doi: 10.3892/ol.2020.12072

Figure 2.

Figure 2.

Combined treatment with DMC increases DDP sensitivity in A549/DDP cells. (A) Treatment of A549/DDP cells with DDP (3.8 µM) and DMC (5 µM). (B and C) A549/DDP cells were treated with high concentrations of DDP (10 and 20 µM) and DMC (5 µM). (D) MRC-5 cells were treated with different concentrations of DMC for 48 h. MRC-5 cells were also treated with single DMC or DDP (0, 2.5, 5, 10, 20, 40 and 80 µM) or the combination of DMC (5, 10 and 20 µM) and different concentrations of DDP (0, 2.5, 5, 10, 20, 40 and 80 µM) for 48 h. *P<0.05, **P<0.01. DMC, demethoxycurcumin; DDP, cisplatin; OD, optical density.