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Combination treatment inhibits A549/DDP cell-derived subcutaneous ectopic tumor growth. (A) Tumor volume was measured from day 0 to day 20 in each group of mice. (B) Tumor weights of A549/DDP xenografts at day 20 following treatment. (C) A549/DDP cell-derived subcutaneous neoplasms on day 20. (D and E) Expression of Ki-67 was detected by immunohistochemistry. Scale bar in (D)=50 µm. *P<0.05, **P<0.01, ****P<0.0001. DDP, cisplatin.
