Table 2.

Drugs targeting HIF/HIF mediated metabolic enzymes

Drug	Target	Tumor	Ref
Atorvastatin	HIF-1α	Burkitt’s Lymphoma	[115]
Oxaliplatin	HIF-1α	Colorectal cancer	[116]
Tamoxifen	HIF-1α	Breast cancer	[109]
Trichostatin A	HIF-1α	Cervical cancer	[117]
Diacetoxyscirpenol	HIF-1α	Liver cancer	[118]
Metformin	HIF-1α	Breast cancer	[119]
Metformin	HIF-1α/GLUT, HK2, PKM, LDH	Cervical cancer	[120]
Ginsenoside Compound K	HIF-1α/PDK1	Lung cancer	[121]
Dovitinib	HIF-1α/GLUT	Lung cancer	[112]
Metformin	HIF-1α/PDH	Oral cancer	[110]
Cetuximab	HIF-1α/LDHA	Head and neck cancer	[111]
Troxacitabine	HIF-1α/PGK	Lung cancer	[122]