Table 2.
Score of UPDRS I-III at W-24, baseline(W0) and W24
| Patient | Score of UPDRS I | Score of UPDRS II | Score of UPDRS III | Total score of UPDRS I-III | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | W-24 | W0 | W24 | ∆W 24-W0 | ∆W0-W-24 | W-24 | W0 | W24 | ∆W 24-W0 | ∆W0-W-24 | W-24 | W0 | W24 | ∆W24-w0 | ∆W0-W-24 | W-24 | W0 | W24 | ∆W 24-w0 | ∆W 0-W-24 |
| 1 | 0.0 | 8.0 | 1.0 | −7.0 | 8.0 | 10.0 | 16.0 | 23.0 | 7.0 | 6.0 | 13.0 | 20.0 | 27.0 | 7.0 | 7.0 | 23.0 | 44.0 | 51.0 | 7.0 | 21.0 |
| 2 | 0.0 | 1.0 | 1.0 | −0.0 | 1.0 | 21.0 | 26.0 | 25.0 | −1.0 | 5.0 | 39.0 | 37.0 | 35.0 | −2.0 | −2.0 | 60.0 | 64.0 | 61.0 | −3.0 | 3.0 |
| 3 | 0.0 | 1.0 | 0.0 | −1.0 | 1.0 | 25.0 | 42.0 | 37.0 | −5.0 | 17.0 | 42.0 | 57.0 | 50.0 | −7.0 | 15.0 | 67.0 | 100.0 | 87.0 | −13.0 | 33.0 |
| 4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 4.0 | 15.0 | 11.0 | −4.0 | 11.0 | 7.0 | 11.0 | 12.0 | 1.0 | 4.0 | 11.0 | 26.0 | 23.0 | −3.0 | 15.0 |
| 5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 19.0 | 19.0 | 22.0 | 3.0 | 0.0 | 21.0 | 29.0 | 33.0 | 4.0 | 8.0 | 40.0 | 48.0 | 55.0 | 7.0 | 8.0 |
| 6 | 0.0 | 1.0 | 1.0 | 0.0 | 1.0 | 35.0 | 38.0 | 37.0 | −1.0 | 3.0 | 58.0 | 63.0 | 60.0 | −3.0 | 5.0 | 93.0 | 102.0 | 98.0 | − 1.0 | 9.0 |
| 7 | 1.0 | 1.0 | 0.0 | −1.0 | 0.0 | 22.0 | 25.0 | 29.0 | 4.0 | 3.0 | 33.0 | 39.0 | 47.0 | 8.0 | 6.0 | 56.0 | 65.0 | 76.0 | 11.0 | 9.0 |
| 8 | 1.0 | 1.0 | 1.0 | 0.0 | 0.0 | 18.0 | 20.0 | 17.0 | −3.0 | 2.0 | 22.0 | 19.0 | 13.0 | −6.0 | −3.0 | 41.0 | 40.0 | 31.0 | −9.0 | −1.0 |
| 9 | 1.0 | 2.0 | 2.0 | 0.0 | 1.0 | 7.0 | 13.0 | 10.0 | −3.0 | 6.0 | 13.0 | 23.0 | 25.0 | 2.0 | 10.0 | 21.0 | 38.0 | 37.0 | −1.0 | 17.0 |
| 10 | 0.0 | 0.0 | 1.0 | 1.0 | 0.0 | 28.0 | 28.0 | 28.0 | 0.0 | 0.0 | 49.0 | 52.0 | 48.0 | −4.0 | 3.0 | 77.0 | 80.0 | 77.0 | −3.0 | 3.0 |
| 11 | 1.0 | 2.0 | 0.0 | −2.0 | 1.0 | 5.0 | 16.0 | 9.0 | −7.0 | 11.0 | 10.0 | 19.0 | 13.0 | −6.0 | 9.0 | 16.0 | 37.0 | 22.0 | −15.0 | 21.0 |
| 12 | 1.0 | 1.0 | 1.0 | 0.0 | 0.0 | 25.0 | 33.0 | 33.0 | 0.0 | 8.0 | 41.0 | 51.0 | 57.0 | 6.0 | 10.0 | 67.0 | 85.0 | 91.0 | 6.0 | 18.0 |
| 13 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 27.0 | 32.0 | 33.0 | 1.0 | 5.0 | 36.0 | 43.0 | 47.0 | 4.0 | 7.0 | 63.0 | 75.0 | 80.0 | 5.0 | 12.0 |
| 14 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 25.0 | 27.0 | 35.0 | 8.0 | 2.0 | 35.0 | 37.0 | 55.0 | 18.0 | 2.0 | 60.0 | 64.0 | 90.0 | 26.0 | 4.0 |
| 15 | 2.0 | 2.0 | 0.0 | −2.0 | 0.0 | 11.0 | 25.0 | 30.0 | 5.0 | 14.0 | 16.0 | 39.0 | 46.0 | 7.0 | 23.0 | 29.0 | 66.0 | 76.0 | 10.0 | 37.0 |
| M± SD | / | / | / | / | / | 18.8 ± 9.4 | 25.0 ± 8.7 | 25.3 ± 9.7 | / | / | 29.0 ± 15.6 | 35.9± 15.6 | 37.9 ± 16.6 | / | / | 48.3 ± 24.5 | 62.3 ± 23.3 | 63.7± 25.8 | / | / |
| t/Z | 1.087a | 2.354b | 0.234a | 2.451b | 1.096a | 2.311b | 0.516a | 2.614b | ||||||||||||
| P | 0.071a | 0.019b | 0.818a | 0.014b | 0.291a | 0.021b | 0.614a | 0.009b | ||||||||||||
“/” means no statistical analysis was performed, “a” means difference between W24 and W0, Paired t test and Wilcoxon rank sum test were performed
“b” means difference of the rate of increase before and after treatment, Wilcoxon rank sum test was performed