Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 10;12:1758835920953728. doi: 10.1177/1758835920953728

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s), 2020

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 6. — HSP70 activates mTOR signaling via AKT to promote pancreatic cancer cell proliferation. (A, B) Flow cytometry analysis of cell apoptosis changes in HSP70 OE MIA-PaCa-2 cells treated with 1 uM MK-2206. (C) CCK-8 assays at 0, 24, 48, 72, 96 h, and (D, E) colony formation assays following culture for 2 weeks showing cell proliferative ability changes in HSP70 OE MIA-PaCa-2 cells treated with 1 uM MK-2206. (F) Western blot analysis of AKT–mTOR signaling changes in HSP70 OE MIA-PaCa-2 cells treated with 1 uM MK-2206.

HSP70, heat shock protein 70; OE, overexpression.

***p-value < 0.001.