Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 4;26:e924453-1–e924453-10. doi: 10.12659/MSM.924453

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Med Sci Monit, 2020

This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

PMC Copyright notice

LY294002 reversed the protective effect of icariin in UA-induced Min6 cell injury. Min6 cells were treated with LY294002, UA and/or icariin for the indicated times. Cells were divided into two groups: UA+20 μM icariin and UA+20 μM icariin+LY294002. (A) Cell viability and (B) apoptosis were assessed using MTT and flow cytometry analysis, respectively. (C) Cell apoptosis. (D) Protein levels of cleaved caspase-3 and pro-caspase-3 measured by western blotting. (E) Secretion of insulin quantified by GSIS. ** P<0.01 compared with the control group; ^# P<0.05, ^## P<0.01 compared with the UA group.