Table 5.

ROC curve parameters of presepsin, PCT alone and in combination with monocyte CD14, PD-L1 and HLA-DR MFI for predicting 28-d mortality in sepsis.

Parameters	AUC	SE	P value	95% confidence interval
				Lower limit	Upper limit
Monocyte CD14 MFI	0.442	0.042	0.177	0.360	0.524
Monocyte PD-L1 MFI	0.509	0.043	0.839	0.424	0.594
Monocyte HLA-DR MFI	0.332	0.040	< 0.001	0.253	0.411
PCT (ng/ml)	0.599	0.043	0.021	0.515	0.683
Presepsin (pg/ml)	0.699	0.041	< 0.001	0.619	0.780
PCT + monocyte CD14 MFI	0.627	0.042	0.003	0.544	0.710
PCT + monocyte PD-L1 MFI	0.590	0.044	0.037	0.504	0.676
PCT + monocyte HLA-DR MFI	0.682	0.040	< 0.001	0.603	0.761
Presepsin + monocyte CD14 MFI	0.691	0.042	< 0.001	0.609	0.773
Presepsin + monocyte PD-L1 MFI	0.701	0.041	< 0.001	0.621	0.782
Presepsin + monocyte HLA-DR MFI	0.727	0.039	< 0.001	0.651	0.803

Statistically significant P-value of less than 0.05 predicting 28-d mortality in sepsis are marked in bold.