Table 2.
The sensitivity, specificity, and accuracy of six diagnostic methods for Mycobacterium tuberculosis complex and nontuberculous mycobacteria compared with BACTEC MGIT 960 system.
| Methods | Sensitivity (95% CI) | Specificity (95% CI) | Accuracy (95% CI) |
|---|---|---|---|
| AFB | 65.2 (42.8–82.8) | 100 (56.1–100) | 73.3 (71.8–74.8) |
| LJ culture | 52.1 (31.1–72.6) | 100 (56.1–100) | 63.3 (61.8–64.8) |
| TB-DNA | 34.8 (17.2–57.2) | 42.9 (11.8–79.8) | 36.7 (34.2–39.2) |
| TB-RNA | 30.4 (14.1−53.0) | 71.4 (30.3–94.9) | 40 (37.5–42.5) |
| T-SPOT | 78.3 (55.8–91.7) | 28.6 (5.1–69.7) | 66.7 (65.3–68.2) |
| Targeted capture sequencing | 91.3 (70.5–98.5) | 42.9 (11.8–79.8) | 83.3(82.3–84.3) |