Figure 7.
TEM analysis of pericyte detachment from the SCBMs in 3 week Alport stria. Strial capillaries from wild type mice show tight adherence between the pericytes and the epithelial/endothelial basement membranes (panels A and C). Alport strial capillaries occasionally show detachment Panels B and D, arrowheads) and less occasionally severe detachment (panel D arrow) with apparent membrane ruffling (panel D asterisks). These anomalies were never observed in the wild type strial capillaries. CL: capillary lumen; EC: endothelial cell; PC: pericyte.