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. 2020 Aug 28;11:911. doi: 10.3389/fneur.2020.00911

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Copyright © 2020 Halász and Szűcs.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Paroxysmal episode druing sleep induced by Ketamine-Xylazine. Recorded by surface and depth EEG from precruciate area 4 and an extracellular ventrolateral (VL) corticothalamic (TC) neuron in cat. (A1) Three paroxysmal episodes separated by 40–45 s. (A2–4) The middle one of the episodes: positive cortical waves followed by spike bursts in the VL initiate the paroxysm. (B) Intracellular recording of a rostral VL cell with SW activity at 2 Hz. (B1,2) Show the close relation between depolarization and field negativities (after Steriade and Contreras).