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. Author manuscript; available in PMC: 2021 Sep 7.
Published in final edited form as: Angew Chem Int Ed Engl. 2020 Jul 16;59(37):15928–15932. doi: 10.1002/anie.202005882

Table 3.

Pd-catalyzed trans-cyanoboration of aryl 1,3-enynes (R2 = Ar)a

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a

Yields of isolated isomerically pure trans product (average of 2 runs), based on 2. The diastereomeric ratio in parenthesis (trans:cis) was determined by 1H NMR of the crude material after addition of 1,8-diaminonaphthalene.

b

15 mol% catalyst loading, 1.2 equiv. CuCN, 1.6 equiv. BCatCl, 90 °C, 25 min.