Table 1.
Baseline characteristics and laboratory parameters of the patients.
| Variables | Normal ascending aortic diameter (n = 99) | Dilated ascending aortic diameter (n = 85) | p value |
|---|---|---|---|
| Age, years | 65.1 ± 9.6 | 65.9 ± 9.0 | 0.60 |
| Sex (male), n (%) | 67 (67) | 54 (53) | 0.55 |
| BMI (kg/m2) | 28.1 (5.1) | 29.4 (6.1) | 0.06 |
| BSA (m2) | 1.9 (0.2) | 1.89 (0.2) | 0.75 |
| Hypertension, n (%) | 61 (61) | 62 (72) | 0.10 |
| Diabetes mellitus, n (%) | 30 (30) | 29 (34) | 0.58 |
| Smoking, n (%) | 24 (24) | 21 (24) | 0.94 |
| Glucose (mg/dL) | 102 (28) | 105 (59) | 0.32 |
| Total cholesterol (mg/dL) | 188.8 ± 42.5 | 175.1 ± 48.1 | 0.04* |
| HDL (mg/dL) | 43 (12.2) | 40.9 (18.3) | 0.01* |
| LDL (mg/dL) | 112.5 ± 37.7 | 101.7 ± 37.6 | 0.05 |
| Triglycerides (mg/dL) | 138 (116) | 126 (96) | 0.49 |
| Creatinine (mg/dL) | 0.82 (0.28) | 0.94 (0.41) | 0.001* |
| GFR (mL/min/ m2) | 88 (26) | 77 (39) | <0.001* |
| Neutrophil (K/uL) | 4370 (1800) | 4450 (2620) | 0.88 |
| Lymphocyte (K/uL) | 2260 ± 776 | 2094 ± 859 | 0.17 |
| NLR | 2.07 (1.35) | 2.1 (2.25) | 0.26 |
| TSH (uIU/mL) | 1.5 (1.5) | 1.4 (1.3) | 0.36 |
| Native thiol (µmol/L) | 439.2 ± 64.6 | 372.1 ± 73.9 | <0.001* |
| Total thiol (µmol/L) | 469.3 ± 64.1 | 403.1 ± 64.1 | <0.001* |
| Disulphide (µmol/L) | 16.2 (12.7) | 15.3 (13.3) | 0.23 |
| Disulphide/Native thiol | 0.04 (0.03) | 0.04 (0.03) | 0.79 |
| Disulphide/Total thiol | 0.03 (0.03) | 0.04 (0.03) | 0.80 |
| Native thiol/Total thiol | 0.93 (0.06) | 0.92 (0.06) | 0.86 |
| Ferroxidase (U/L) | 465 (186) | 498(210) | 0.12 |
| IMA (ABSU) | 75.7 ± 4.3 | 75.2 ± 5.9 | 0.53 |
BMI: Body mass index; BSA: Body surface area; GFR: Glomerular filtration rate; HDL: High-density lipoprotein; IMA: Ischemic modified albumin; IQR: Interquartile range; LDL: Llow-density lipoprotein; NLR: Neutrophil to lymphocyte ratio; SD: Standard deviation; TSH: Thyroid stimulating hormone. Parameters were expressed as mean ± SD and median [IQR].
*P < 0.05 was considered significant for statistical analyses.