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Prevalence of all side effects of colchicine and reasons for drug discontinuation.
| Side effect (n) | All side effects N = 172* |
Permanent cessation N = 18* |
|---|---|---|
| Diarrhea | 99 | 11 |
| Liver toxicity | 54 | 4 |
| Leukopenia | 10 | 1 |
| Muscle toxicity | 5 | 2 |
| Skin reaction | 2 | - |
| Nausea | 4 | - |
| Infertility | 2 | - |
* some patients had more than one clinically significant side effect
