Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model for how Pat1 increases specificity and assembly for different mRNA decay factors. (A) Proposed thermodynamic coupling between Pat1 (blue), Lsm1–7 (red), and RNA binding to promote multimerization of the Pat1/Lsm1–7 complex. (B) Binding of oligomeric Pat1 assemblies to multivalent Dcp1/Dcp2 (purple) complexes promotes phase separation and recruitment of additional mRNA decay factors.
