Table 1.
Patients with Advanced Stage NSCLC in NCDB from 1998–2012, surgically treated compared to non-surgically treated using Chi-Square tests.
| Variable | Nonsurgical Patients N= 281,871 (94%) | Surgical Patients N= 18,701 (6%) | p-value |
|---|---|---|---|
| AJCC Stage Group | |||
| IIIA | 47,525 (16.9) | 10,650 (56.9) | P<0.0001 |
| IIIB | 51,603 (18.3) | 3,483 (18.6) | |
| IV | 182,743 (64.8) | 4,568 (24.4) | |
| Histology | |||
| NSCLC | 83,826 (29.7) | 3,184 (17.0) | |
| Squamous Cell Ca | 75,487 (26.8) | 6,171 (33) | |
| Adenocarcinoma | 122,558 (43.5) | 9,346 (49.9) | |
| Tumor Size | |||
| 1a | 26,654 (9.5) | 2,945 (15.8) | P<0.0001 |
| 1b | 42,176 (14.9) | 3,590 (19.2) | |
| 2a | 91,140 (32.3) | 5,735 (30.7) | |
| 2b | 64,377 (22.8) | 3,480 (18.6) | |
| 3 | 57,524 (20.4) | 2,951 (15.8) | |
| AJCC T Status | |||
| 1 | 36,946 (13.11) | 3,875 (20.7) | P<0.0001 |
| 2 | 82,382 (29.2) | 6,273 (33.5) | |
| 3 | 39,958 (14.2) | 3,277 (17.5) | |
| 4 | 97,944 (34.8) | 4,458 (23.8) | |
| X | 24,641 (8.7) | 818 (4.4) | |
| AJCC N Status | |||
| 0 | 44,503 (15.8) | 4,117 (22) | P<0.0001 |
| 1 | 23,775 (8.4) | 2,430 (12.9) | |
| 2 | 131,743 (46.7) | 10,201 (54.6) | |
| 3 | 50,664 (17.9) | 850 (4.6) | |
| X | 31,186 (11.1) | 1,103 (5.9) | |
| AJCC M Status | |||
| 0 | 103,413 (36.7) | 14,269 (76.3) | P<0.0001 |
| 1 | 133,452 (47.4) | 3,530 (18.9) | |
| 1A | 11,226 (3.9) | 331 (1.8) | |
| 1B | 33,780 (11.9) | 571 (3.1) | |
| Charlson Index | |||
| 0 | 176,275 (62.5) | 10,978 (59.7) | P<0.0001 |
| 1 | 73,277 (26) | 5,743 (30.8) | |
| 2 | 32,319 (11.5) | 1,980 (10.6) | |
| Age | |||
| 0–52 | 27,384 (9.7) | 2,592 (13.9) | P<0.0001 |
| 52–59 | 40,071 (14.2) | 3,350 (17.9) | |
| 59–67 | 65,500 (23.2) | 5,122 (27.4) | |
| 67–75 | 71,840 (25.5) | 4,675 (24.5) | |
| 75–81 | 44,609 (15.8) | 2,170 (11.6) | |
| >81 | 32,467 (11.5) | 702 (3.8) | |
| Race | |||
| White | 236,598 (83.9) | 16,321 (87.3) | P<0.0001 |
| Black | 36,736 (13) | 1,847 (9.9) | |
| Other | 8,537 (3.0) | 533 (2.9) | |
| Facility Type | |||
| Community Cancer Program | 38,445 (13.6) | 1,906 (10.2) | P<0.0001 |
| Comprehensive Community Cancer Program | 160,635 (56.9) | 10,022 (53.6) | |
| Academic/Research Program | 82,791 (29.4) | 6773 (36.2) | |
| Insurance | |||
| Not Insured | 13,691 (4.9) | 578 (3.1) | P<0.0001 |
| Private Insurance | 84,181 (29.9) | 7915 (42.3) | |
| Medicaid | 21,701 (7.7) | 1,224 (6.6) | |
| Medicare | 158,253 (56.1) | 8,737 (46.7) | |
| Other Government | 4,045 (1.4) | 247 (1.3) | |
| Income | |||
| Low | 59,661 (21.2) | 3,478 (18.6) | P<0.0001 |
| Middle | 76,594 (27.2) | 4,757 (25.4) | |
| High | 145,616 (51.7) | 10,466 (55.9) |