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Effect of dose and dosing frequency on rifapentine exposure. (A) Rifapentine concentration over time and (B) concentration over time in log scale in a typical individual without HIV infection following once-daily, thrice-weekly, twice-weekly, and once-weekly administration of 600 mg (orange), 900 mg (green), or 1,200 mg (blue). The black dashed lines show the minimum inhibitory concentration (equal to 0.06 mg/L).
