Table 5.
Geometric parameters of the docking poses along with biological activities of sulfonamides.
| Compound | O(Ser195)····C=O(pivaloyl) (Å) | IC50 (μM) |
|---|---|---|
| 3a | 3.05 | 0.030 |
| 7b | 6.74 | 5.2 |
| 7d | 5.40 | 0.086 |
| 7e | 5.96 | 0.460 |
| Sivelestat | 3.04 | 0.044 |
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