Table 1.
A) Meta-analysis results for poor treatment outcomes, studies on drug-susceptible TB
Treatment outcome | Studies n | Summary effect estimate | 95% CI | I2 % | P value heterogeneity |
---|---|---|---|---|---|
Poor outcome A* | 25 | 1.99 | 1.57–2.51 | 93 | <0.001 |
Poor outcome B† | 12 | 2.55 | 1.77–3.66 | 23 | 0.222 |
Death | 22 | 1.58 | 1.24–2.00 | 73 | <0.001 |
Treatment failure | 13 | 3.12 | 1.83–5.33 | 52 | 0.014 |
LTFU | 29 | 2.25 | 1.74–2.91 | 79 | <0.001 |
B) Meta-analysis results for poor treatment outcomes, studies on multidrug-resistant TB | |||||
---|---|---|---|---|---|
Treatment outcome | Studies n | Summary effect estimate | 95% CI | I2 % | P value heterogeneity |
Poor outcome A* | 18 | 2.00 | 1.73–2.32 | 32 | 0.098 |
Poor outcome B† | 10 | 1.47 | 1.06–2.05 | 64 | 0.003 |
Death | 6 | 1.38 | 1.04–1.83 | 0 | 0.551 |
Treatment failure | 4 | 1.54 | 1.09–2.17 | 45 | 0.143 |
LTFU | 15 | 1.87 | 1.56–2.24 | 51 | 0.013 |
Death, treatment failure, and LTFU.
Death and treatment failure.
TB = tuberculosis; CI = confidence interval; LTFU = loss to follow-up.