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editorial
. 2020 Sep 15;14(6):751–755. doi: 10.1016/j.jacl.2020.09.002

Table 1.

Study populations’ anxiety level, attitude and behavioral changes since the emergence of the outbreak with regard to access to lipid apheresis and use of additional new-generation lipid-lowering agents

Questionnaire items Replies All HoFH Patients lost access to LA session due to COVID-19 pandemic
All group No additional new-generation LLT use Additional new-generation LLT use
N 34 14 7 7
Any complaint, n (%) - 3 (8.8) 1 (7.1) 1 (14.3) 0
Use of medicines regularly, n (%) - 30 (88.2) 12 (85.7) 5 (71.4) 7 (100)
Working during the epidemic, n (%)
  • a

    working from home

  • b

    working

  • c

    no

 1 (2.9)
3 (8.8)
30 (88.2)		 0
0
14 (100)		 0
0
7 (100)		 0
0
7 (100)
Increase in anxiety, n (%) - 21 (61.8) 9 (64.3) 6 (85.7) 3 (42.9)
Anxiety level, ∗ mean ± SD (minimum–maximum) - 4.79 ± 2.57 (0-9) 4.93 ± 2.26 (2-8) 5.14 ± 2.12 (2-8) 4.71 ± 2.56 (2-8)
Sleep, n (%)
  • a

    sleeping less

  • b

    sleeping more

  • c

    no change

 6 (17.6)
6 (17.6)
22 (64.7)		 3 (21.4)
2 (14.3)
9 (64.3)		 2 (28.6)
1 (14.3)
4 (57.1)		 1 (14.3)
1 (14.3)
5 (71.4)
Appetite, n (%)
  • a

    eating less

  • b

    eating more

  • c

    no change

 5 (14.7)
8 (23.5)
21 (61.8)		 4 (28.6)
1 (7.1)
9 (64.3)		 3 (42.9)
0
4 (57.1)		 1 (14.3)
1 (14.3)
5 (71.4)
Dietary compliance, n (%)
  • a

    better

  • b

    worse

  • c

    no change

 20 (58.8)
5 (14.7)
9 (26.5)		 9 (64.3)
0
5 (35.7)		 5 (71.4)
0
2 (14.3)		 4 (57.1)
0
3 (42.9)
Exercise habits, n (%)
  • a

    better

  • b

    worse

  • c

    no change

 8 (23.5)
17 (50)
9 (26.5)		 4 (28.6)
7 (50)
3 (21.4)		 2 (28.6)
3 (42.9)
2 (66.7)		 2 (28.6)
4 (57.1)
1 (14.3)
Smoking, n (%)
  • a

    nonuser

  • b

    more

  • c

    less

  • d

    no change

 27 (79.4)
1 (2.9)
4 (11.8)
2 (5.9)		 12 (85.7)
0
2 (14.3)
0		 6 (85.7)
0
1 (14.3)
0		 6 (85.7)
0
1 (14.3)
0
Thought of increased vulnerability within the course of COVID-19 due to underlying FH, n (%)
  • a

    yes

  • b

    no

  • c

    do not know

 27 (79.4)
5 (14.7)
2 (5.9)		 11 (78.6)
2 (14.3)
1 (7.1)		 7 (100)
0
0		 4 (57.1)
2 (28.6)
1 (14.3)
Have admitted to a hospital during the pandemic? n (%) - 9 (26.5) 3 (21.4) 0 3 (42.9)
Would admit to a hospital due to a complaint, n (%) - 9 (26.5) 2 (14.3) 0 2 (14.3)

FH, familial hypercholesterolemia; LA, LDL apheresis; LLT, lipid-lowering therapy; SD, standard deviation.

∗

The anxiety level for all samples has a skewed distribution; the median level is 5.