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Histological grading of colitis in DSS-induced colitis mice
| Score | Inflammation | Extent | Crypt damage | Percent involvement (%) |
|---|---|---|---|---|
| 0 | None | None | None | None |
| 1 | Slight | Mucosa | Basal 1/3 damaged | 1-25% |
| 2 | Moderate | Mucosa and sub-mucosa | Basal 2/3 damaged | 26-50% |
| 3 | Severe | Transmural | Only surface epithelium intact | 51-75% |
| 4 | Entire crypt and epithelium lost | 76-100% |
