Table 2.
Results of immune-morphometric measurements of Bax, Bcl2, Bax/Bcl2 ratio (apoptotic body index; ABI) for liver tissue of different treated groups
Parameters | Bax positive area % | Bcl2 positive area% | Bax/Bcl2 Ratio (ABI) |
---|---|---|---|
Groups | |||
Vehicle | 6.23 ± 0.09 | 41.57 ± 1.3 | 0.1 |
Rotenone | 31.4 ± 0.24* | 18.06 ± 0.76* | 1.73 |
Rotenone + amphetamine 0.5 mg/kg | 22.5 ± 0.11*+ | 19.62 ± 1.19*+ | 1.14 |
Rotenone + amphetamine 1 mg/kg | 18.37 ± 0.66*+ | 25.04 ± 1.55*+ | 0.73 |
Rotenone + amphetamine 2 mg/kg | 6.5 ± 1.06* | 36.02 ± 0.82* | 0.18 |
Data were expressed as mean±SE. Statistical analysis was carried out by one-way ANOVA. *: P<0.05 vs vehicle. +: P<0.05 vs rotenone control