Figure 1.

Effects of α-lapachone and β-lapachone on cell migration and wound healing. (A) Effects of α-lapachone on the migration rate of epidermal keratinocytes. (B) Average wound size in α-lapachone treated cells plotted as a bar graph. (C) Effects of β-lapachone on the migration rate of epidermal keratinocytes. (D) Average wound size in β-lapachone treated cells plotted as a bar graph. Values are means±SEM. ∗∗∗P<0.001 VS vehicle group. (E) Effects of α-lapachone on wound healing in mice. (F) Graphical representation of the effects of α-lapachone on wound healing in mice. (G) Effects of β-lapachone on wound healing in mice. (H) Graphical representation of the effects of β-lapachone on wound healing in mice. Values are means±SEM (n = 5/group). ∗∗P<0.01, ∗∗∗P<0.001 VS vehicle at different time points