Table 1.

Characteristics of studies of disorders and traits included in the analyses

Phenotype	Study	Year	Data source	Sample size (cases/controls)	Study design	Effect size	Ancestry
ADHD	DeMontis et al21	2017	PGC, iPSYCH	20,183/35,191	Case‐control	OR	European
Alcohol dependence	Walters et al37	2018	PGC	10,206/28,480	Case‐control	OR	European
Cannabis dependence	Agrawal et al38	2018	PGC	3,757/9,931	Case‐control	Beta	European
Tobacco use	Furberg et al26	2010	PGC, TGC	73,853	Continuous	Beta	European
Aggression	Pappa et al30	2016	EAGLE	18,988	Continuous	Beta	European
Antisocial behavior	Tielbeek et al28	2017	BroadABC	16,400	Continuous	Beta	European
Eating disorders	Duncan et al24	2017	PGC	3,495/10,982	Case‐control	OR	European
Anxiety disorders	Otowa et al27	2016	PGC, ANGST	7,016/14,745	Case‐control	Beta	European
PTSD	Duncan et al24	2017	PGC	2,424/7,113	Case‐control	OR	European
MDD	Wray et al1	2018	PGC, iPSYCH	59,851/113,154	Case‐control	OR	European
OCD	Arnold et al25	2017	PGC, IOCDF‐GC, OCGAS	2,688/7,037	Case‐control	OR	European
Schizophrenia	Ripke et al2	2014	PGC	36,989/113,075	Case‐control	OR	Admixed
Bipolar disorder	Stahl et al3	2019	PGC	20,352/31,358	Case‐control	OR	European
ASD	Grove et al22	2019	PGC, iPSYCH	18,382/27,969	Case‐control	OR	European

ADHD – attention‐deficit/hyperactivity disorder, PTSD – post‐traumatic stress disorder, MDD – major depressive disorder, OCD – obsessive‐compulsive ‐disorder, ASD – autism spectrum disorder, PGC – Psychiatric Genetics Consortium, iPsych – Lundbeck Foundation Initiative for Integrative Psychiatric ‐Research, EAGLE – Early Genetics and Lifecourse Epidemiology, BroadABC – Broad Antisocial Behavior Consortium, ANGST – Anxiety NeuroGenetics Study, IOCDF‐GC – International Obsessive Compulsive Disorder Foundation Genetics Collaborative, OCGAS – OCD Collaborative Genetics Association Studies, TGC – Tobacco and Genetics Consortium, OR – odds ratio, beta – standardized regression coefficient