Table 3. Bi-variable and multivariable Cox regression analysis to identify the predictors of LTFU among HIV-infected children receiving ART at Debre-Markos Referral Hospital, Northwest Ethiopia, 2019.
| Variables | Survival status | CHR (95%CI) | AHR (95%CI) | |
|---|---|---|---|---|
| Lost | Censured | |||
| Residence | ||||
| Urban | 28 | 248 | 1 | 1 |
| Rural | 42 | 90 | 3.6(2.3, 5.9) | 3.2(2.0, 5.3)** |
| Religion of the caregiver | ||||
| Orthodox | 66 | 283 | 1 | 1 |
| Others | 4 | 55 | 0.31(0.1, 0.9) | 0.5 (0.2, 1.5) |
| Relation of caregiver to the child | ||||
| Parent | 64 | 284 | 1 | 1 |
| Other guardians | 6 | 54 | 0.5(0.2, 1.1) | 1.1(0.4, 2.8) |
| ART drug adherence | ||||
| Good | 40 | 281 | 1 | 1 |
| Fair/poor | 30 | 57 | 2.6(1.6, 4.1) | 2.7(1.4, 5.5)** |
| ART eligibility criteria | ||||
| Immunologic and clinical | 55 | 286 | 1 | 1 |
| Test and treat | 15 | 52 | 2.6(1.4, 4.6) | 2.7(1.4, 5.5) ** |
| Baseline ART regimen | ||||
| NVP and EFV based | 59 | 311 | 1 | 1 |
| PI based | 11 | 27 | 3.8(1.9, 7.3) | 2.2(1.1, 4.4)** |
| WHO clinical staging | ||||
| Stage I and II | 31 | 181 | 1 | 1 |
| Stage III and IV | 39 | 157 | 1.3 (0.8, 2.2) | 1.2 (0.7, 2.1) |
| CD4 counts | ||||
| Below the threshold | 43 | 233 | 1 | 1 |
| Above the threshold | 27 | 103 | 1.5(0.9, 2.4) | 1.5(0.8, 2.6) |
| Wasting | ||||
| Wasted | 47 | 261 | ||
| Normal | 23 | 77 | 1.5(0.9, 2.5) | 1.3(0.8, 2.2) |
| OI prophylaxis given | ||||
| Yes | 28 | 200 | 1 | 1 |
| No | 22 | 138 | 0.7(0.4–1.2) | 0.8(0.47, 1.4) |
**significant variables in the multivariable analysis.