Table 1.
Syndromic form of cleft lip and palate
| Syndromes | Gene name (symbol) | Location on chromosome | Inheritance |
|---|---|---|---|
| Waardenburg syndrome, type II A | Microphtalmia associated transcription(MLTF) | 3p14,1-12,3 | AD |
| Di George syndrome | Di George syndrome chromosome region (CATCH 22) | 22g11 | AD |
| Treacher - Collins mandibulofacialdysostosis | Treacle (TCOF1) | 5q32-q33,1 | AD |
| Van der woude syndrome | Interferor regulatory factor - 6 (IRF 6) | 1q32-q41 | AD |
| CLP-Ectodermal dysplasia syndrome | Poliovirus receptor related-1(PVRL-1) | 11q23,3 | AD |
| Ectrodactyly, ectodermal dysplasia orofacial cleft syndrome | P 63 | 3q27 | AD |
| Zollinger syndrome-3 | Peroxisomalmembrame protein-3 (PXMP3) | 8q21,1 | AD |
| Diastrophic dysplasia | Diastrophic dysplasia sulphate transporter(DTDST) | 5q32-q33,1 | AD |
| Gorlin syndrome (Basal cell nevus syndrome) | Patched (PTCH) | 9q22,3 | AD |