Table 2.
Possible genes whose mutation may result in non syndromic clefting
| Name of gene | Symbol | Chromosome location |
|---|---|---|
| Transforming growth factor - alpha | TGFA | 2p13 |
| Transforming growth factor - 133 | TGF 133 | 14q24 |
| Methylene tetra - hydrofolateReductase | MTHF3 | 1p36,3 |
| Blood clotting factor XIII gene | ET1 | 6p24 |
| Endothelin - 1 gene | ET1 | 6p24 |
| Proto-oncogene BCL3 | BCL3 | 19q13,2 |
| Retinoic acid receptor alpha gene | RARA | 17(t15/17) |
| MSX-1 | MSX-1 | 4q25 |